A broad-spectrum penicillin, Polyflex (ampicillin trihydrate), is active against a wide range of common gram-positive and gram-negative bacteria. It effectively treats respiratory tract infections, such as shipping fever in beef and dairy cattle and calves, including vealers. It has a six-day pre-slaughter withdrawal and a 48-hour milk withdrawal period after the last treatment. Polyflex also provides effective treatment for urinary tract, gastrointestinal, and skin (soft tissue) infections in cats and dogs.
In all species, 3 days treatment is usually adequate,
but treatment should be continued for 48 to 72 hours after the animal
has become afebrile or asymptomatic.
The multi-dose dry-filled vials should be reconstituted to the desired concentration by adding the required amount of Sterile Water for Injection, USP, according to label directions. SHAKE WELL.
After reconstitution this product is stable for 3 months under refrigeration will be white to pale yellow in color. At the time of reconstitution the vial should be dated and the concentration noted on the label.
A history of allergic reactions to penicillin,
cephalosporins or their analogues should be considered a
contraindication for the use of this agent.
Do not treat cattle for more than 7 days. Milk from
treated cows must not be used for food during treatment, and for 48
hours (4 milkings) after the last treatment. Cattle must not be
slaughtered for food during treatment, and for 144 hours (6 days) after
the last treatment.
Because it is a derivative of 6-aminopenicillanic acid,
Polyflex has the potential for producing allergic reactions. If they
should occur, Polyflex should be discontinued and the subject treated
with the usual agents (antihistamines, pressor amines, corticosteroids).