Veterinarian Prescription (Rx) Required
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Give Spironolactone with food to lessen stomach upset. Keep plenty of water available for your pet.
Spironolactone is a water pill (potassium-sparing diuretic) available by prescription that is used to treat edema, high blood pressure, potassium deficiency, and hyperaldosteronism.
Spironolactone is used to reduce the amount of fluid in the body without also causing loss of potassium.
Pet | Weight | Dosage |
Dogs | All Weights | The usual dose in dogs and cats is 0.5 mg - 1 mg per pound of body weight every 12 hours |
Cats | All Weights | The usual dose in dogs and cats is 0.5 mg - 1 mg per pound of body weight every 12 hours |
Spironolactone Hydrochlorothiazide should not be used in pets with hyperkalemia (high potassium levels), Addison's disease, kidney failure, severe renal failure or significant renal impairment. It should be used cautiously in animals with hepatic (liver) disease, but is often used to treat ascites (accumulation of fluid in the peritoneal cavity, which causes abdominal swelling).
This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.
Please contact your veterinarian if you notice any of the following reactions: dehydration with excessive thirst and decreased urine production, or electrolyte imbalances, possibly with weakness, lethargy, restlessness, stumbling, dizziness, muscle pain or cramping, lack of energy, vomiting and diarrhea.