Dorzolamide HCL inhibits carbonic anhydrase II. Inhibition of carbonic
anhydrase decreases aqueous humor secretion, presumably by slowing the
formation of bicarbonate ions with subsequent reduction in sodium and
fluid transport. The result is a reduction in intraocular pressure
(IOP).
Dorzolamide HCL Sterile Ophthalmic Solution is a prescription
medication used in dogs and cats to reduce pressure inside the eye by
reducing the amount of fluid in the eye.
Dorzolamide HCL Sterile Ophthalmic Solution is also used to treat high blood pressure in the eye due to open-angle glaucoma.
Dorzolamide HCL Sterile Ophthalmic Solution is a prescription
medication not FDA approved for veterinary use; however, it is a
commonly accepted practice for veterinarians to prescribe this
medication for dogs and cats.
Tip: Do not touch the dropper to any surface, including
eyes and hands. The dropper is sterile. If it becomes contaminated, it
could cause an infection of the eye. Do not use if the eye drop is
discolored or has particles in it. Dorzolamide HCL Sterile Ophthalmic
Solution may cause blurred vision.
Dosage:
Pet |
Weight |
Dosage |
Dogs/Cats: |
All weights |
The usual dose is 1 drop in the eye 3 times a day. Apply this
medication to the pet’s eye by pushing the “Finger Push Area” of the
dropper bottle which then releases a single drop of the medication. If
you are using any other eye drop in your pet’s eye, wait 10 minutes
between the use of different medications |
Horses: |
X |
X |
Storage: Store this product at room temperature, away from moisture and heat. Keep the tube properly capped.
|
Ingredients:
Dorzolamide HCL:
Active Ingredients (per mL) |
Amount |
Dorzolamide Hydrochloride |
22.3 mg per ml |
Preservative
Benzalkonium Chloride |
0.0075% |
|
Other Ingredients:
Hydroxyethyl Cellulose, mannitol, sodium citrate dihydrate, sodium hydroxide (to adjust pH) and water for injection.
|
What happens if I miss giving a dose:
Apply the missed dose as soon as you remember. However, if it is almost
time for the next regularly scheduled dose, skip the missed dose and
apply the next one as directed. Do not use a double dose of this
medication.
What happens if I overdose the pet:
Symptoms of Dorzolamide HCL overdose are not known but may include
panting, diarrhea, vomiting and loss of appetite which can occur when
using oral carbonic anhydrase inhibitors. If an overdose is suspected,
flush the eye with water and call your veterinarian or veterinary
emergency room.
What should I avoid while giving Dorzolamide HCL to my pet:
Dorzolamide HCL may cause blurred vision. Do not touch the dropper to
any surface, including the eyes and hands. If it becomes contaminated,
it could cause an infection in the eye. If you are using another eye
drop in your pet, wait 10 minutes between use of different medications.
Possible side effects of Dorzolamide HCL:
If any of the following serious side effects occur, stop using this
Dorzolamide HCL and seek emergency veterinary medical attention; an
allergic reaction (swelling of the lips, face, or tongue; difficulty
breathing; closing of the throat; or hives). Less serious side effects
may be more likely to occur. Continue to use Dorzolamide HCL and contact
your veterinarian if your pet experiences itching or watering of the
eye; blurred vision; sensitivity of the eye to sunlight; fatigue; rash;
or nausea. Side effects other than those listed here may also occur.
Talk to your veterinarian about any side effect that seems unusual or
bothersome to the animal.
What other drugs will affect Dorzolamide HCL:
Tell your veterinarian if your pet is being given an oral carbonic
anhydrase inhibitor such as acetazolamide (Diamox), dichlorphenamide
(Daranide), or methazolamide (Neptazane). Avoid applying other topical
medications at the same time unless told to by the veterinarian. Other
topical medications may affect the absorption or effectiveness of
Dorzolamide HCL. Drugs other than those listed may also interact with
Trusopt. Talk to your veterinarian or pharmacist before giving any
prescription or over the counter medications, including vitamins,
minerals, and herbal products.
What should I discuss with my veterinarian before giving Dorzolamide HCL to my pet:
Tell your veterinarian if your pet has ever had an allergic reaction to a
sulfa based drug such as SMZ/TMP (bactrim, Septra), sulfisoxazole,
sulfamethoxazole, or sulfacetamide sodium (Bleph-10), Sulamyd Sodium).
Dorzolamide HCL is based on a sulfa compound and your pet may have an
allergic reaction to it. Tell your veterinarian if your pet has kidney
or liver disease. Tell your veterinarian if your pet is pregnant,
lactating, or if you intend to breed your pet.
Cautions:
Disclose all medications you are giving to your pet to your
veterinarian. If any side effects occur (swelling, hives, difficulty
breathing), stop using Dorzolamide HCL on your pet and contact your
veterinarian. Do not touch the dropper to any surface, including the
eyes and hands. If it becomes contaminated, it could cause an infection
in the eye.