Mexiletineis a class 1B sodium channel blocker. An anti-arrhythmia drug which is used to treat chronic ventricular arrhythmias in dogs.
Mexiletine is a class 1B sodium channel blocker used to treat heart conditions in small animals. It is used to treat ventricular arrhythmias and has similar mechanism or activity to lidocaine.
Mexiletine is used to treat seriously irregular heartbeats
For Dogs
What is Mexiletine Hydrochloride Capsule?
Mexiletine is a class 1B, sodium channel blocker, anti-arrhythmia drug which is used to treat chronic ventricular arrhythmias in dogs. The mechanism of action is similar to lidocaine. Mexiletine is used to treat ventricular arrhythmias including PVC’s and ventricular tachycardia. If an animal has responded well to lidocaine during an acute episode, it is likely to respond well to mexiletine.
Why use Mexiletine Hydrochloride Capsule?
Treats ventricular arrhythmias in dogs
Similar to lidocaine
Used to treat ventricular arrhythmias including PVC's and ventricular tachycardia
Mexiletine may be combined with either atenolol or sotalol in instances when monotherapy is not adequate.
Mexiletine may be used to treat inherited cardiomyopathy in Boxers and dilated cardiomyopathy in Doberman pinschers.
A positive response to therapy would be an 85% reduction of ventricular premature contractions.
How does Mexiletine Hydrochloride Capsule work?
Mexiletine is well absorbed orally and has a bioavailability of approximately 85%. It is primarily excreted in the urine although approximately 10% is metabolized by the liver and excreted in the feces. The half-life of this drug may be prolonged in animals with reduced cardiac output, or after an acute myocardial infarction. The half-life may also be prolonged in animals with hepatic dysfunction or severe kidney disease.
How to Use
Pet
Weitht
Dosage
Dogs
All weights
Use as directed by your veterinarian.
Cats
All weights
Use as directed by your veterinarian.
Active Ingredient(s)
MEXILETINE HYDROCHLORIDE (MEXILETINE)
How is Mexiletine Hydrochloride Capsule sold?
Mexiletine is sold in single 150, 200, and 250 mg capsules.