Clindamycin HCl 25 mg per mL Oral Drops

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Description

Clindamycin Hydrochloride Oral Drops for Dogs and Cats is indicated for the treatment of infections caused by susceptible strains of:

Skin infections in dogs (wounds and abscesses) due to coagulase positive staphylococci (Staphylococcus aureus or Staphylococcus intermedius). 

Deep wounds and abscesses in dogs due to Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

Dental infections in dogs due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

Osteomyelitis in dogs due to Staphylococcus aureus, Bacteroides fragilis, Prevotella melaninogenicus, Fusobacterium necrophorum and Clostridium perfringens.

Skin infections in cats (wounds and abscesses) due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp.

Deep wounds and abscesses in cats due to Clostridium perfringens and Bacteroides fragilis.

Dental infections in cats due to Staphylococcus aureus, Staphylococcus intermedius, Streptococcus spp., Clostridium perfringens and Bacteroides fragilis.

Contraindications

Clindamycin Hydrochloride Oral Liquid is contraindicated in animals with history  of hypersensitivity to preparations containing clindamycin or lincomycin. Because of the potential adverse gastrointestinal effects, do not administer to rabbits, hamsters, guinea pigs, horses, chinchillas or ruminating animals. 

 

Precautions

During prolonged therapy of one month or greater, periodic liver and kidney function tests and blood counts should be performed.

The use of clindamycin hydrochloride occasionally results in overgrowth of non-susceptible organisms such as clostridia and yeasts. Therefore, the administration of clindamycin hydrochloride should be avoided in those species sensitive to the gastrointestinal effects of clindamycin. Should superinfection occur, appropriate measures should be taken as indicated by the clinical situation.

Patients with severe renal disease and/or very severe hepatic disease accompanied by severe metabolic aberrations should be dosed with caution, and serum clindamycin levels monitored during high dose therapy.

Clindamycin hydrochloride has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, clindamycin hydrochloride should be used with caution with animals receiving such agents. Safety in gestating female dogs and female cats or breeding male dogs and cats has not been established.

Dosage and Administration

Dogs (Infected wounds, abscesses and dental infections)

Oral

2.5-15.0mg/lb body weight every 12 hours.

Duration

Treatment with clindamycin hydrochloride products may be continued up to a maximum of 28 days if clinical judgment indicates. Treatment of acute infections should not be continued for more than three or four days if no response to therapy is seen. 

Dogs (Osteomyelitis) 

Oral

5.0-15.0 mg/lb body weight evey 12 hours 

Duration

Treatment with Clindamycin Hydrochloride Oral Liquid is recommended for a minimum of 28 days. Treatment should not be continued for longer than 28 days if no response to therapy is seen.

Cats (Infected wounds abscesses and dental infections)

Oral

5.0-15.0mg/lb body weight once every 24 hours depending on the severity of the condition.

Duration

Treatment may be continued up to a maximum of 14 days if clinical judgement indicates. Treatment of acute infections should not be continued for more than three to four days if no clinical response to therapy is seen.

Dosage Schedule

Clindamycin Hydrochloride Oral Liquid, to provide 5.0mg/lb, administer 1mL/5 lb body weight once every 24 hours; to provide 15.0mg/ml, administer 3mL/5lb body weight once every 24 hours.  

How Supplied

Available as a 20mL filled in 30mL bottles (25mg/mL).

Warnings

Keep out of reach of children. Not for human use.