How to Order Prescriptions

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Description

INCURIN® (estriol) Tablets treat female canine urinary incontinence (bladder control issues). Incurin® contains estriol, a naturally occurring, short-acting estrogen found in female dogs.

Benefits

• 93% of dogs treated were improved or continent by 6 weeks

• Convenient, once-a-day dosing

• One simple starting dose for all female dogs and just 1 tablet size to stock

• Titrated to the lowest effective dose

Active Ingredients

Contains 1mg/tablet oestriol.  
 

Dosage

Incurin is intended for once daily oral administration. 

 

The following dosing schedule is advised

• 1 tablet (1mg) per day for 7-14 days.

If the treatment with 1 tablet daily is effective, try to reduce the dose to the minimum possible with 7 days treatments.

• ½ tablet per day then ½ tablet every other day
• If the treatment with 1 tablet daily is ineffective, increase the dose to 2 tablets daily for 7 days. If this is effective, then try to reduce the dose to 2 tablets every other day.
• Proven effective in reducing or eliminating urinary incontinence1

If these are ineffective, then go see your veterinary to reassess case to confirm the diagnosis, then consider supplementary therapy.

Treatment will continue for the remainder of the life of the dog.

Important Safety Information

Incurin is indicated for the control of estrogen-responsive urinary incontinence in ovariohysterectomized dogs. The most common side effects associated with Incurin treatment under field conditions included loss of appetite, vomiting, excessive water drinking, and swollen vulva. The safety and effectiveness of Incurin Tablets have not been evaluated in dogs less than 1 year of age, intact female dogs, male dogs, dogs used for breeding, or lactating dogs. Incurin is contraindicated in dogs showing polyuria secondary to polydipsia, or in pregnant dogs. Please see the product label for full prescribing information.


Incurin Tablets for Dogs is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.

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by Merck

Active Ingredients:  
Contains 1mg/tablet oestriol.  
      
Indications: 
For the treatment of hormone-responsive urinary incontinence due to sphincter mechanism incompetence in female dogs.

Dosage
Incurin is intended for once daily oral administration.  There is no relationship between the size of the dog and the dose required, so a fixed mg/kg dose rate is not feasible.
Effectiveness is defined as no signs of incontinence for 7 consecutive days.  An improvement will usually be noticed within a few days.  However, adjustment of the initial dose will often be necessary, so at least 7 days should be allowed before judging the full effect of a certain dose rate.

The following dosing schedule is advised:
Initial dose:   1 tablet (1mg) per day for 7-14 days.
(a) If treatment with 1mg daily is effective, try to reduce the dose to the minimum possible with 7 days treatment as follows:
½ tablet/day, then
½ tablet on alternate days
If treatment is ineffective at the lower doses, titrate back to the next lowest dose.
(b) If treatment with 1mg daily is ineffective, increase the dose to 2mg daily for 7 days.  (Maximum dose should not exceed 2mg/day).  If effective, try reducing dose to 2mg on alternate days.  However, if treatment with 2mg/day is ineffective, reassess case to confirm diagnosis, then consider supplementary therapy.

Treatment will continue for the remainder of the life of the dog.

Prescription Animal Remedy (P.A.R) Class I. For use only under the authority or prescription of a veterinarian.